Students
Selected Senior Theses
Creation of a proU::LEE5 hybrid gene to elucidate the regulatory mechanism of Ler in Enteropathogenic Escherichia coli
by Trevor Young, May 2007
The CfaR Positive Regulator of Colonization Factor Antigen I (CFA/I) Pili is Important for Enteropathogenic Escherichia coli Infection of the Nematode Caenorhabditis elegans
by Rebecca J. Kreston, May 2007
Understanding Virulence: in vitro Analysis of H-NS and Ler Mediated
Regulation of the LEE5 Regulatory Region in Enteropathogenic Esherichia
coli.
by Anna M. Carmona, May 2006
Regulation of Enteropathogenic Escherichia coli Virulence Genes by the SOS Response
by Derek C. Galligan, May 2005
The Enteropathogenic Escherichia coli global regulator Ler is critical to pathogenesis in the nematode Caenorhabditis elegans
by Alex M. Barron, May 2005
Characterization of the C-terminal Binding Domain of Ler
by Katharine L. Horback, May 2004.
Colonization of Caenorhabditis elegans by Enteropathogenic E. coli
by Andrew S. Korson, May 2004
Reversible Frameshift mutations in the perA gene of Escherichia coli
by Rebecca S. Bart, May 2003
Interactions of Environmental and Transcriptional Factors in Regulation of Enteropathogenic Escherichia coli Virulence Genes
by Alhaji Ceesay, May 2003
Sucrose Utilization in Enteropathogenic E. coli
by Kristin Harper, May 2002
Ler and H-NS Medited Transcriptional Regulation of the LEE5 Operon of Enteropathogenic E. coli
by Jonathan W. Fowlkes, December 2002
Ler Mediated Regulation of the Tir Operon in Enteropathogenic E. coli by Footprinting and Deletion Analysis
by Kristie J. Miller, May 2001
Sucrose Metabolism in Pathogenic E. coli
by Leslie A. Hoover, May 2001
Thesis students from my lab have been accepted into graduate programs at various schools, such as Emory University, the University of California at Davis, the University of California, Berkeley, School of Public Health, and the University of Michigan; medical schools such as the University of Maryland School of Medicine; and gained employment at biotechnology companies such as MedImmune, Inc., and Biovest International.
Presentations
Mellies, JL, Larabee, F,Haack, K, and D Mavor. The Ler Linker Domain Is Essential for Anti-Silencing Activity in Enteropathogenic Escherichia coli. Presented at the Molecular Genetics of Bacteria and Phage Meeting,
Madison, WI, August 7-12, 2007.
Kreston, RJ, Barron, MS and JL Mellies. Using the Nematode Caenorhabditis elegans to Model Enterotoxigenic Escherichia coli Infection. Presented at the General Meeting of the American Society for Microbiology, Toronto, Canada, May 20-25, 2007.
Mellies, JL, Haack, K and DC Galligan. SOS Regulation of the Type III Secretion System of Enteropathogenic Escherichia coli. Presented at the Gordon Research Conference on Microbial Stress Response, Mt. Holyoke College, South Hadley, Massachusetts, July 9-13, 2006.
Carmona, A.M., Glasfeld, A., and JL Mellies. Molecular Mechanism of LEE5 Transcription in Enteropathogenic Escherichia coli: in vitro Analysis of H-NS and Ler Binding. Presented at the Northwest Branch Meeting of the American Society for Microbiology, Seattle, Washington, March 10-12, 2006.
Barron, A, Haack, K, and JL Mellies. Caenorhabditis elegans as a Model for Enteropathogenic Escherichia coli Infection. Presented at the General Meeting of the American Society for Microbiology, Atlanta, Georgia, June 5–9, 2005.
Galligan, D, Haack, K, and JL Mellies. Regulation of EPEC Virulence Genes by DNA Damage Signaling. Presented at the General Meeting of the American Society for Microbiology, Atlanta, Georgia, June 5–9, 2005.
Barron, A, Galligan, D , and JL Mellies. Caenorhabditis elegans as a Model Host for Enteropathogenic Escherichia coli (EPEC) Pathogenesis. Presented at the Northwest Branch Meeting of the American Society for Microbiology, Vancouver, British Columbia, Canada, August 8-10, 2003.
Mellies, JL, Ceesay, A, Fowlkes, J, and Haack, K. Ler and H-NS Mediated Regulation of the LEE5 (tir) Operon in Enteropathogenic E. coli. Presented at the General Meeting of the American Society for Microbiology, Washington, D.C., May 18-22, 2003.
Harper, KN and L Hoover, K Haack, I Okeke and JL Mellies. Sucrose Utilization in Enteropathogenic E. coli. Presented at the General Meeting of the American Society for Microbiology, Salt Lake City, Utah, May 19-23, 2002
Mellies, JL, CL Robinson, K Haack, K Miller, and K Harper. Mechanism of Ler-Mediated Activation of tir in Enteropathogenic E. coli. Presented at the General Meeting of the American Society for Microbiology, Salt Lake City, Utah, May 19-23, 2002.
Awards
Anna Carmona ('06)
Best Undergraduate Research Poster Presentation at the Northwest Branch
Meeting of the American Society for Microbiology, Seattle, Washington,
March 10-12, 2006.
Alex Barron ('05)
Student Travel Award - ASM General Meeting, Atlanta, Georgia, June 2005
Derek Galligan ('05)
ASM Undergraduate Research Fellowship, 2004-2005
Kristin Harper ('02)
Student Travel Award - ASM General Meeting, Salt Lake City, Utah, May 2002
NSF Graduate Fellowship ('03) and Howard Hughes Medical Institute Pre-Doctoral Fellowship ('03)
Leslie Hoover ('01)
NIH Post-Baccalaureate Research Fellowship, Bethesda, Maryland, 2001-2003
