Reed College
Biology Department
Portland, OR 97202
Office B106
Lab B104
tel. 503-777-7220
fax. 503-777-7773
email: yeast@reed.edu
Teaching Fall of 2010:
Biology
361: Genetics
Teaching Spring of 2011:
Biology 431: Molecular Biology of the Gene (seminar course)
Biology 431: Molecular Virology (seminar course)
Information |
Research Projects
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We are a molecular genetics lab. using budding yeast, Saccharomyces cerevisiae (photo below) as a model host to identify and characterize host genes involved in pathogenic RNA plant virus gene expression and replication.
Our general research goal is to obtain an understand of virus-host interactions at the molecular level. Specifically, we are studying Barley yellow dwarf virus (BYDV), which is a plant pathogenic, single-stranded RNA virus. Our primary research focuses are: 1) to identify and characterize host genes for the virus sequence-programmed stop-codon readthrough event involved in expression of the capsid proteins of this virus; and 2) to establish a replication system in yeast with which to identify host gene for viral genome replication.
Researchers in the Lab.
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Anita Bennett - Senior Research Assistant
Reed College undergraduate researchers:
- 2010 summer student: Andrew Lyon
- 2009/2010 thesis students: Andrew Lyon, Seyram Tsagli, Nicholas Wilson
- 2009 summer students: Saate Shakil, Jeanette Tenthorey
- 2009 (spring) independent research student: Andrew Lyon
- 2008 summer student: Andrew Lyon
- 2007/2008 thesis student: Rachel Bond
An upper-division genetics lecture/laboratory course, a molecular biology of the gene seminar course, a molecular virology seminar course, and advising senior thesis research students and independent research students.
Related to my teaching, I am the author of a genetics textbook that has gone through eight editions. The present edition is iGENETICS: A MOLECULAR APPROACH (3e). Related versions are iGENETICS: A MENDELIAN APPROACH (1e) ( (c) 2006, Benjamin/Cummings) and ESSENTIAL iGENETICS ( (c) 2003). I am also one of the authors of an introductory biology textbook, BIOLOGY: A DYNAMIC SCIENCE (1e), by Russell, Wolfe, Hertz, and Starr ((c) 2008, Thomson/Brooks Cole); the second edition of this textbook will be published December 2010. Covers of some of the books are below.
iGenetics
(3e) iGenetics
(2e) Biology
(1e) Biology (2e)
EDUCATION/FACULTY APPOINTMENTS
SELECTED RESEARCH PUBLICATIONS
EDUCATION/FACULTY APPOINTMENTS
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section]
B.Sc., University of Sussex in Biology, 1968
Ph.D., Cornell University in Genetics, 1972
Biology faculty of Reed College, 1972–present; currently Professor of Biology (Genetics).
SELECTED RESEARCH PUBLICATIONS
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Bennett, A. M., A. R. Norris, A. Limnander de Nieuwenhove & P. J. Russell. 2002. Replication of a linear mini-chromosome with terminal inverted repeats from the Kluyveromyces lactis linear DNA plasmid k2 in the cytoplasm of Saccharomyces cerevisiae. Plasmid 48:13-23.
Russell, P. J., A. M. Bennett, Z. Love, & D. M. Baggott. 1997. Cloning, sequencing and expression of a full-length cDNA copy of the M1 double-stranded RNA virus from the yeast, Saccharomyces cerevisiae. Yeast 13:829-836.
Russell, P. J., S. J. Hambidge, & K. Kirkegaard, 1991. Direct introduction and transient expression of capped and non-capped RNA in Saccharomyces cerevisiae. Nucl. Acids Res. 19:4949-4953.
Court, D. A., A. J. F. Griffiths, S. R. Kraus, P. J. Russell & H. Bertrand, 1991. A new senescence-inducing mitochondrial linear plasmid in field-isolated Neurospora crassa strains from India. Curr. Genet. 19:129-137.
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2010
LYON, ANDREW. Expression and replication of Barley yellow dwarf virus RNA replicons in Saccharomyces cerevisiae.
2008
BOND, RACHEL. Promoter-regulated effects of TIS11 overexpression
on the rate of Barley yellow dwarf virus stop codon readthrough in
Saccharomyces cerevisiae.
2007
CAMPBELL, AMY. The effect of mutated host ribosomal protein genes
on Barley yellow dwarf virus stop codon readthrough in
Saccharomyces cerevisiae.
2006
CHEN, HSIN-CHIEH (Candy). The effect of STU2 overexpression on
Barley yellow dwarf virus (BYDV) ORF 3 stop codon readthrough
efficiency in Saccharomyces cerevisiae.
CORAY, DORIEN SKYE. What does this have to do with goats:
Identifying host genes involved in stop codon readthrough in
Barley yellow dwarf virus.
SWANSON, LINDSAY. Effects of overexpressed host genes
STU2 and YHR213W-A on Barley yellow dwarf virus stop codon
readthrough in Saccharomyces cerevisiae.
2005
BOECK, MAX. A cellular pirate's sword: Identification of two yeast tRNA genes
that enhance Barley yellow dwarf virus's programmed stop codon readthrough event.
NEWTON, KELLY. Identification of host factors involved in Barley yellow dwarf
virus programmed stop codon readthrough in the model organism, Saccharomyces
cerevisiae.
SKORCHEVA, ILIYANA. Effects of a distal viral sequence and of an overexpressed
host gene on Barley yellow dwarf virus stop codon readthrough in yeast.
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Click HERE to learn of activities I do outside of research and teaching.
Maintained by the Reed College Biology Department
Last Modified July 2010
Questions/Comments to yeast@reed.edu