Week Three - Sept. 10-14, 2007

Reading: 
    Lecture notes on circular dichroism and fluorescence spectroscopy.
    Lecture notes on folding studies and secondary structure.

Online:
    Thermodynamics notes from electronic textbook on Biophysics (more mathematical than my treatment, but pretty accessible.)

Powerpoints:
    My powerpoint movies of plane-polarized light, optical rotation and circular dichroism.

Online:
    Horst Schirra's Intro to NMR: Skim 2-5, look over 7 & 8 more carefully.

Literature refs: good review of issues in protein stability.
    Pace et al. (2004) Protein structure, stability and solubility in water and other solvents Phil. Trans. R. Soc. Lond. B 359, 1225-1235.