Tuesday - Serine & Aspartyl Proteases

Reading

Voet and Voet, Chapter 15

Optional: Branden and Tooze, Ch. 11 (on reserve)

 

Thursday - Metals and Lewis Acid Catalysis

Reading

Voet and Voet - Ch. 15.1C

My notes on the topic.

Berg and Lippard, Principles of Bioinorganic Chemistry, Chapter 2. (On Reserve)

D. Christianson (1999) Catalysis by Metal Activated Hydroxides in Zinc and Manganese Metalloenzymes. Annu. Rev. Biochem. 68 33-57. Focus on carbonic anhydrase after reading introductory material.